3,211 research outputs found

    Volume and surface propellant heating in an electrothermal radio-frequency plasma micro-thruster

    Get PDF
    The temporal evolution of neutral gas temperature over the first 5 min of operation for an electrothermal radio-frequency micro-thruster with nitrogen (N2) propellant was measured using rovibrational band matching of the second positive N2 system. Three distinct periods of gas heating were identified with time constants of τ 1 = 8 × 10⁻⁵ s, τ 2 = 8 s, and τ 3 = 100 s. The fast heating (τ 1) is attributed to volumetric heating processes within the discharge driven by ion-neutral collisions. The slow heating (τ 3) is from ion neutralization and vibrational de-excitation on the walls creating wall heating. The intermediate heating mechanism (τ 2) is yet to be fully identified although some theories are suggested.This research was partially funded by the Australian Space Research Program (APT project) and the Australian Research Council Discovery Project (No. DP140100571)

    Emulating Simulations of Cosmic Dawn for 21cm Power Spectrum Constraints on Cosmology, Reionization, and X-ray Heating

    Full text link
    Current and upcoming radio interferometric experiments are aiming to make a statistical characterization of the high-redshift 21cm fluctuation signal spanning the hydrogen reionization and X-ray heating epochs of the universe. However, connecting 21cm statistics to underlying physical parameters is complicated by the theoretical challenge of modeling the relevant physics at computational speeds quick enough to enable exploration of the high dimensional and weakly constrained parameter space. In this work, we use machine learning algorithms to build a fast emulator that mimics expensive simulations of the 21cm signal across a wide parameter space to high precision. We embed our emulator within a Markov-Chain Monte Carlo framework, enabling it to explore the posterior distribution over a large number of model parameters, including those that govern the Epoch of Reionization, the Epoch of X-ray Heating, and cosmology. As a worked example, we use our emulator to present an updated parameter constraint forecast for the Hydrogen Epoch of Reionization Array experiment, showing that its characterization of a fiducial 21cm power spectrum will considerably narrow the allowed parameter space of reionization and heating parameters, and could help strengthen Planck's constraints on σ8\sigma_8. We provide both our generalized emulator code and its implementation specifically for 21cm parameter constraints as publicly available software.Comment: 22 pages, 9 figures; accepted to Ap

    Recombining your way out of trouble: the genetic architecture of hybrid fitness under environmental stress

    No full text
    Hybridization between species is a fundamental evolutionary force that can both promote and delay adaptation. There is a deficit in our understanding of the genetic basis of hybrid fitness, especially in non-domesticated organisms. We also know little about how hybrid fitness changes as a function of environmental stress. Here, we made genetically variable F2 hybrid populations from two divergent Saccharomyces yeast species, exposed populations to ten toxins, and sequenced the most resilient hybrids on low coverage using ddRADseq. We expected to find strong negative epistasis and heterozygote advantage in the hybrid genomes. We investigated three aspects of hybridness: 1) hybridity, 2) interspecific heterozygosity, and 3) epistasis (positive or negative associations between non-homologous chromosomes). Linear mixed effect models revealed strong genotype-by-environment interactions with many chromosomes and chromosomal interactions showing species-biased content depending on the environment. Against our predictions, we found extensive selection against heterozygosity such that homozygous allelic combinations from the same species were strongly overrepresented in an otherwise hybrid genomic background. We also observed multiple cases of positive epistasis between chromosomes from opposite species, confirmed by epistasis- and selection-free simulations, which is surprising given the large divergence of the parental species (~15% genome-wide). Together, these results suggest that stress-resilient hybrid genomes can be assembled from the best features of both parents, without paying high costs of negative epistasis across large evolutionary distances. Our findings illustrate the importance of measuring genetic trait architecture in an environmental context when determining the evolutionary potential of hybrid populations

    Studies in the vegetational history of Greece

    Get PDF
    The vegetational history of Greece was studied by means of pollen analysis. Six pollen diagrams from various parts of the Greek mainland are presented, which between them cover a time from around 30,000 years ago to the present day. The development of the vegetation from a steppe during the time of the last glaciation through a transitional stage in the late-glacial period to a post-glacial forest, and the degradation of the vegetation to the present day scrub is represented by three main pollen assemblage zones. Zone I covers part or all of the time of the last glacial period when the dominant vegetation was an Artemisia steppe with little woodland, in response to a cool dry climate with a temperature comparable with that of northern Europe today but probably less rainfall than is usual in Greece now. Zone II covers the vegetational development during the time of the late-glacial and early post-glacial where evidence from southern Greece shows a pioneer scrub vegetation being succeeded by mixed-oak forest in response to a temperature and rainfall increase, with a temporary reversion to cool and dry conditions deduced from a vegetational reversion. This sequence probably corresponds to the lower Dryas-Allerd-Upper Dryas sequence known in northern Europe. Zone III covers the degradation of the forest vegetation which appears to have taken place earlier in southern Greece than in the north, where there appears to have been substantial forest up to at least the year A.D. and possibly until Medieval times before clearance by man and animal. Two periods of olive cultivation are recognisable, one in Middle Bronze Age – Mycenean times and the other in Late Dark Ages – Early Classical times. There is no sign of climatic change in the Post-glacial sequence. The pollen rain from some modern Greek vegetation shows that tara which are abundant there may be seriously under-represented in the pollen rain

    Saccharomyces cerevisiae: a nomadic yeast with no niche?

    Get PDF
    Different species are usually thought to have specific adaptations, which allow them to occupy different ecological niches. But recent neutral ecology theory suggests that species diversity can simply be the result of random sampling, due to finite population sizes and limited dispersal. Neutral models predict that species are not necessarily adapted to specific niches, but are functionally equivalent across a range of habitats. Here we evaluate the ecology of S. cerevisiae, one of the most important microbial species in human history. The artificial collection, concentration, and fermentation of large volumes of fruit for alcohol production produces an environment in which S. cerevisiae thrives, and therefore it is assumed that fruit is the ecological niche that S. cerevisiae inhabits and has adapted to. We find very little direct evidence that S. cerevisiae is adapted to fruit, or indeed to any other specific niche. We propose instead a neutral nomad model for S. cerevisiae, which we believe should be used as the starting hypothesis in attempting to unravel the ecology of this important microbe

    Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators

    Get PDF
    This Letter was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Scottish Universities Life Sciences Alliance (SULSA) in 2011Peer reviewedPostprin

    Direct measurement of neutral gas heating in a radio-frequency electrothermal plasma micro-thruster

    No full text
    Direct measurements and modelling of neutral gas heating in a radio-frequency (13.56 MHz) electrothermal collisional plasma micro-thruster have been performed using rovibrational band matching of the second positive system of molecular nitrogen (N2) for operating pressures of 4.5 Torr down to 0.5 Torr. The temperature measured with decreasing pressure for 10 W power input ranged from 395 K to 530 K in pure N2 and from 834 K to 1090 K in argon with 1% N2. A simple analytical model was developed which describes the difference in temperatures between the argon and nitrogen discharges.Aspects of this research made use of software developed by the Inversion Laboratory (ilab). Ilab is part of the Auscope AGOS project—an initiative of the Australian Government funded through the Education Investment Fund

    Exchange anisotropy pinning of a standing spin wave mode

    Full text link
    Standing spin waves in a thin film are used as sensitive probes of interface pinning induced by an antiferromagnet through exchange anisotropy. Using coplanar waveguide ferromagnetic resonance, pinning of the lowest energy spin wave thickness mode in Ni(80)Fe(20)/Ir(25)Mn(75) exchange biased bilayers was studied for a range of IrMn thicknesses. We show that pinning of the standing mode can be used to amplify, relative to the fundamental resonance, frequency shifts associated with exchange bias. The shifts provide a unique `fingerprint' of the exchange bias and can be interpreted in terms of an effective ferromagnetic film thickness and ferromagnet/antiferromagnet interface anisotropy. Thermal effects are studied for ultra-thin antiferromagnetic Ir(25)Mn(75) thicknesses, and the onset of bias is correlated with changes in the pinning fields. The pinning strength magnitude is found to grow with cooling of the sample, while the effective ferromagnetic film thickness simultaneously decreases. These results suggest that exchange bias involves some deformation of magnetic order in the interface region.Comment: 7 pages, 7 figure
    corecore